WATCH TRAILER OF THIS FILM HERE

This film begins where The Bourne Identity leaves off. It substantially deviates from the underlying book as Alexander Conklin is now dead and the CIA is Bourne's enemy rather than his friend (the plot actually incorporates aspects of the Bourne novel The Bourne Legacy written by Eric Van Lustbader as well). This movie does not follow the Robert Ludlum novel The Bourne Supremacy, which takes place in Hong Kong with Marie getting kidnapped so Bourne will accept a mission.
This film continues the theme of its predecessor including substantial mystery albeit in a more politically dramatic, double-sided atmosphere. It also ends the romantic sub-plot but subtly increases the emotional side of the Bourne character by further exploring his care for children.
In The Bourne Identity Jason Bourne fails an assassination and gains amnesia as a result of it. Not knowing who he is, he is hunted by a CIA black ops organization called Treadstone which trains and manages expert assassins. Bourne slowly discovers he was one of these assassins and manages to sever his relationship with this organization by the end of the film, warning Treadstone of serious consequences should the CIA attempt to follow him. He also gains a companion, Marie Helena Kreutz, but fails to learn of his identity prior to his involvement in Treadstone or any additional information regarding himself including any past operations he may have been a part of.